St. John's Wort is a popular herb around the world and often used for mood and depression. It is allegedly able to improve serotonin levels, and also seems to affect GABA and dopamine levels. St. john's wort may also increase the number and density of serotonin receptors over time, although more studies are needed. When people are low on these neurotransmitters, St. john's wort may be able to balance these levels and improve mood. Many doctors recommend anti-depressant medication to people suffering with mood disorders, but research shows a long list of possible side effects such as cardiac issues, suicidal thoughts, sexual side effects, nausea, dizziness, and other possible short and long term issues. (1,2) St. john's wort has an excellent safety profile according to an abundance of studies.
St. John's wort is one of the best compounds for healing damaged nerves. This is actually one of St. john's wort's strengths, and not very well known. St. john's wort may also help fight chronic inflammation by lowering certain cytokines and factors that negatively impact overall health and increase the chances of certain diseases forming. Studies show that it may also help decrease the anxiety and mood swings in menopausal women and alleviate the severity of PMS symptoms. It may also help alleviate cravings to addictive substance to some degree. One study with 12 people with obsessive compulsive disorder showed benefits to most participants. In addition, St. john's wort interferes with angiogenesis, which helps to fight cancer. (3-5)
Suggested use 300-400mgs twice per day