Coffee berry extract is a unique extract that uses the whole fruit of the coffee plant, and has different attributes than the coffee bean. It is relatively new to the market, and extensive testing hasn't been done just yet, but luckily there's some research showing safety and medicinal value. We carry a 10:1 extract for a full spectrum of nutrients, while still being medicinally potent. One of the medicinally attractive attributes seen in testing so far is it's incredible antioxidant rating. It has shown to outperform the antioxidant scores of potent nutrients like white and green tea, blueberries, pomegranate, and other powerful antioxidant rich fruits and herbs. (1) Some say it's actually one of the most antioxidant rich substances in the world. The reason for this is because of the high altitude, low latitude areas where the sun's rays are incredibly strong and defense mechanisms (antioxidants) are produced for survival. (2)
One small study showed that coffee berry stimulated a neural protein called brain derived neurotrophic factor, or BDNF. (3) BDNF has been shown to influence nerve growth, synaptic plasticity, neurotransmitter release, axon growth, which all play crucial roles in learning, memory, and behavior. (4) Low levels of BDNF have been seen in conditions such as obsessive compulsive disorder, Alzheimer's disease, dementia, and depression. Another study done with coffee berry showed that it decreased free radicals like peroxides, superoxide, hydroxyl radical, and singlet oxygen. (5)
Coffee berry may also confer benefits to those suffering with diabetes. The polyphenols in coffee berry may help damaged pancreatic beta cells and improve glucose levels. Some of the polyphenols in coffee berry such as chlorogenic acid, caffeic acid, trigonelline, quinic acid, polysacharrides, and ferulic acid have research showing quite a wide range of medicinal value. In one human clinical trial at the Moscow Modern Medical Center, chlorogenic acid helped reduce blood glucose levels by 15-20%! (6) In another study done at the National Cheng Kung University in Taiwan on caffeic acid, it was clearly shown that it increased glucose uptake into cells. (7,8) Coffee berry's benefits also likely extend to the cardiovascular system by protecting arterial and heart cells from harmful molecules.
Suggested use- 250-300mgs twice per day.
References
- http://thedermblog.com/2008/04/03/5-reasons-why-you-should-look-for-coffeeberry/
- http://nutritionvalue.blogspot.com/2012/05/most-powerful-fruit-on-planet.html
- http://www.nutraingredients-usa.com/Research/Coffee-fruit-extract-shows-potential-brain-benefits-FutureCeuticals-study
- http://pharmrev.aspetjournals.org/content/64/2/238.full
- http://www.coffeeberry.com/initial-research-0
- Hemmerle H, Burger HJ, Below P, et al. Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase. J Med Chem. 1997 Jan 17;40(2):137-45
- Cheng JT, Liu IM. Stimulatory effect of caffeic acid on alpha1A-adrenoceptors to increase glucose uptake into cultured C2C12 cells. Naunyn Schmiedeberg’s Arch Pharmacol. 2000 Aug;362(2):122-7.
- Hsu FL, Chen YC, Cheng JT. Caffeic acid as active principle from the fruit of Xanthium strumarium to lower plasma glucose in diabetic rats. Planta Med. 2000 Apr;66(3):228-30
